COMPARATIVE ANALYSIS OF THE EFFICACY OF BIOCOMPATIBLE AND HIGH-EFFICIENCY HYDROXYAPATITE-BASED PASTES IN TREATMENT OF DENTIN HYPERENSITIVITY
Keywords:
Dentin Hypersensitivity, Hydroxyapatite, Biocompatible, Desensitizing Paste, Biomimetic, Clinical Trial, Tubule Occlusion.Abstract
Dentin hypersensitivity (DH) is a common and painful clinical condition characterized by short, sharp pain arising from exposed dentin in response to various stimuli. The search for effective, biocompatible, and long-lasting desensitizing agents remains a key focus in modern dentistry. Hydroxyapatite (HAp)-based pastes have emerged as a promising treatment due to their biomimetic properties, which allow them to occlude dentinal tubules and integrate seamlessly with the natural tooth structure.
References
1. Addy M. Dentin hypersensitivity: new perspectives on an old problem. Int Dent J. 2002;52(5):367-375.
2. Brännström M. A hydrodynamic mechanism in the transmission of pain-producing stimuli through the dentine. In: Anderson DJ, ed. Sensory Mechanisms in Dentine. Pergamon Press; 1963:73-79.
3. West NX, Lussi A, Seong J, Hellwig E. Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin. Clin Oral Investig. 2013;17(Suppl 1):S9-S19.
4. Cummins D. Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief. Am J Dent. 2010;23(Spec No A):3A-13A.
5. Roveri N, Foresti E, Lelli M, Lesci IG. Recent advancements in preventing teeth health hazards: the use of biomimetic hydroxyapatite. Nanomedicine (Lond). 2009;4(8):965-974.
6. Kim MJ, Lee SH, Lee NY, Lee IH, Lee SH, Kim JS. The effect of nano-hydroxyapatite toothpaste on dentin hypersensitivity: a randomized clinical trial. J Dent Hyg Sci. 2019;19(1):63-71.
7. Kim S, Jeong J, Jang S, et al. Remineralization effects of nano-hydroxyapatite and fluoride on artificial enamel lesions: an in vitro study. Materials (Basel). 2021;14(16):4615.
8. Pashley DH. How can sensitive dentine become hypersensitive?. J Clin Periodontol. 2013;40(Suppl 14):S16-S22.
9. Pepla E, Besharat LK, Palaia G, Tenore G, Migliau G. Nano-hydroxyapatite and its applications in preventive, restorative and regenerative dentistry: a review of literature. Ann Stomatol (Roma). 2014;5(3):108-114.