GANODERMA LUCIDUM EXTRACT IN GASTROENTEROLOGICAL DISEASES
Keywords:
Ganoderma lucidum, gastroenterology, dysbiosis, immunity, antioxidants, microbiocenosis, ulcer disease, probiotics.Abstract
This scientific article investigates the effectiveness of Ganoderma lucidum extract in gastroenterological diseases, particularly ulcerative disorders accompanied by intestinal dysbiosis. The study evaluated the influence of the extract on intestinal microbiocenosis, immunological status, antioxidant defense system, and psychoemotional condition of patients. The findings demonstrated that Ganoderma lucidum extract normalized intestinal microflora, reduced inflammatory mediators, and improved immune system activity. In addition, enhancement of antioxidant activity and improvement in patients’ quality of life were observed. The obtained results confirm that Ganoderma lucidum extract represents a promising therapeutic agent in the комплекс treatment of gastroenterological pathologies.
References
1. Soll A.H. Peptic ulcer and its complications. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Philadelphia; 2018. Vol.1. P.620–678.
2. Abelo A., Andersson T.B., Antonsson M., et al. Stereo-selective metabolism of omeprazole by human cytochrome P450 enzymes. Drug Metabolism and Disposition. 2020;28(8):966–972.
3. Hudson N., Brydon W.G., Eastwood M.A., et al. Successful H. pylori eradication incorporating a one-week antibiotic regimen. Alimentary Pharmacology & Therapeutics. 2015;9:47–50.
4. Suzuki S., Esaki M., Kusano C., et al. Vonoprazan-based triple therapy vs PPI-based triple therapy as first-line treatment. Gut. 2017;66(9):1724–1732.
5. Talley N.J., Venables V.T., Green J.R., et al. Esomeprazole in long-term management of gastro-oesophageal reflux disease. European Journal of Gastroenterology & Hepatology. 2012;14(8):857–863.
