COMPARATIVE IMMORPHOLOGICAL INDICATORS OF THE THYMUS OF WHITE RATS IN FE DEFICIENCY.
Keywords:
Keywords: iron deficiency, thymus, white rat, lymphopoiesis, T-lymphocytes, immune system.Abstract
Annotation As a result of histological analysis of the lymphoid structures of the thymus in white outbred rats with alimentary iron deficiency, a violation of parenchymal-stromal balance in the organ, a decrease in the morphometric parameters of lymphoid tissue, the number of lymphoid cells, and the level of expression of immunohistochemical markers were revealed. In immunohistochemical studies, a significant decrease in the expression of markers CD3, Ki-67, and Bcl-2 was noted, which means that iron deficiency negatively affects the proliferation, differentiation, and immunocompetence of T-lymphocytes.
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