Propargil spirti va ikkilamchi aminlar asosida sintez qilingan mahsulotdan olingan moddalarning efirlarini olish texnalogiyasi
Keywords:
A³-coupling, propargil spirti, dietilamin, CuSO₄ katalizatori, organik sintez, iminium ioni, reduktiv aminlanish.Abstract
Ushbu maqola 4-dietilaminobut-2-in-1-ol birikmasining sintezi bo'yicha laboratoriya tajribasini taqdim etadi. Sintez A³-coupling reaksiyasi asosida amalga oshirilgan bo'lib, paraformaldehid, propargil spirti va dietilamin reagentlari CuSO₄ katalizatori ishtirokida 1,4-dioksan erituvchisida 84°C haroratda 7 soat davomida o'tkazilgan. Reaksiya mexanizmi iminium ioni hosil bo'lishi va metallasetilidning nukleofilik hujumini o'z ichiga oladi. Olingan mahsulot suv va HCl bilan neytrallangan holda ajratilgan bo'lib, hosildorlik 70-95% ni tashkil etadi. Ushbu usul organik sintezda propargilamin va aminospirtlar olish uchun samarali yondashuv hisoblanadi.
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