METABOLIC FACTORS CONTRIBUTING TO THE DEVELOPMENT OF INSULIN RESISTANCE IN CHILDREN

Authors

  • ABDUMANNOBOVA RUSHANA OLIMJON QIZI
  • IRISKULOV B.U Professor, Doctor of Sciences (DSc)
  • AXMEDOVA D.B Doctor of Sciences (DSc) Tashkent state medical university, Tashkent, Uzbekistan

Keywords:

insulin resistance, metabolic syndrome, pediatric obesity, lipid profile, leptin, glucose tolerance.

Abstract

Childhood obesity has become a pressing global epidemic, closely linked to the early onset of metabolic syndrome and insulin resistance (IR). This thesis investigates the specific metabolic factors driving IR in school-aged children. Based on a cross-sectional clinical and laboratory analysis of 131 children, the study reveals severe metabolic disruptions, including hyperinsulinemia, atherogenic dyslipidemia, and hyperleptinemia, highlighting the urgent need for early targeted interventions.

References

1. World Health Organization (2016). Global status report on noncommunicable diseases.

2. Abdumannobova, R. O. (2026). Risk factors of insulin resistance in school-aged children (Dissertation).

3. Tagi, V. M., Giannini, C., & Chiarelli, F. (2019). Insulin resistance in children. Frontiers in Endocrinology.

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Published

2026-03-25

How to Cite

ABDUMANNOBOVA RUSHANA OLIMJON QIZI, IRISKULOV B.U, & AXMEDOVA D.B. (2026). METABOLIC FACTORS CONTRIBUTING TO THE DEVELOPMENT OF INSULIN RESISTANCE IN CHILDREN. INTEGRATION OF EDUCATION AND SCIENCE: GLOBAL CHALLENGES AND SOLUTIONS, 2(03), 124–125. Retrieved from https://worldconferences.us/index.php/iesg/article/view/1110