THE DIAGNOSTIC VALUE OF COLPOSCOPY IN CERVICAL PATHOLOGIES
Keywords:
colposcopy, cervical pathology, cervical intraepithelial neoplasia (CIN), human papillomavirus (HPV), acetic acid test, directed biopsy, squamous intraepithelial lesion (SIL).Abstract
This thesis evaluates the diagnostic efficacy of colposcopy in the early detection and management of cervical pathologies. By analyzing colposcopic findings and correlating them with histological outcomes, the study demonstrates that colposcopy is an indispensable clinical tool that bridges the gap between initial screening and definitive diagnosis. The findings emphasize that colposcopically directed biopsies significantly increase the accuracy of detecting cervical intraepithelial neoplasia (CIN) and early invasive cancer, thereby optimizing patient outcomes and preventing disease progression.
References
1. Massad, L. S., Einstein, M. H., Huh, W. K., Katki, H. A., Kinney, W. K., Schiffman, M., ... & Lawson, H. W. (2013). 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. Journal of Lower Genital Tract Disease, 17(5), S1-S27.
2. Sellors, J. W., & Sankaranarayanan, R. (2003). Colposcopy and treatment of cervical intraepithelial neoplasia: a beginners' manual. International Agency for Research on Cancer.
3. Darragh, T. M., Colgan, T. J., Cox, J. T., Heller, D. S., Henry, M. R., Luff, R. D., ... & Wilkinson, E. J. (2012). The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Archives of Pathology & Laboratory Medicine, 136(10), 1266-1297.
4. Arbyn, M., Sasieni, P., Meijer, C. J., Clavel, C., Koliopoulos, G., & Dillner, J. (2006). Chapter 9: Clinical applications of HPV testing: a summary of metaanalyses. Vaccine, 24(3), S78-S89.
